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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P29536
USC-OGP 2-DE database
:
P29536
P29536
General information about the entry
View entry in simple text format
Entry name
LMOD1_HUMAN
Primary accession number
P29536
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Leiomodin-1; AltName: Full=64 kDa autoantigen 1D; AltName: Full=64 kDa autoantigen 1D3; AltName: Full=64 kDa autoantigen D1 {ECO:0000303|PubMed:2026759}; AltName: Full=Leiomodin, muscle form; AltName: Full=Smooth muscle leiomodin; Short=SM-Lmod; AltName: Full=Thyroid-associated ophthalmopathy autoantigen;.
Gene name
Name=LMOD1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1147
:
pI=4.85; Mw=55709
Cross-references
UniProtKB/Swiss-Prot
P29536; LMOD1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
LMOD1_HUMAN
Primary accession number
P29536
Secondary accession number(s)
B1APV6 C4AMB1 Q68EN2
Sequence was last modified on
March 8, 2011 (version 3)
Annotations were last modified on
March 15, 2017 (version 139)
Name and origin of the protein
Description
RecName: Full=Leiomodin-1; AltName: Full=64 kDa autoantigen 1D; AltName: Full=64 kDa autoantigen 1D3; AltName: Full=64 kDa autoantigen D1 {ECO:0000303|PubMed:2026759}; AltName: Full=Leiomodin, muscle form; AltName: Full=Smooth muscle leiomodin; Short=SM-Lmod; AltName: Full=Thyroid-associated ophthalmopathy autoantigen;
Gene name
Name=LMOD1
Encoded on
Name=LMOD1
Keywords
3D-structure
;
Actin-binding
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Repeat
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X54162; CAA38101.1
; -; mRNA
EMBL
AL513217; CAH72278.2
; -; Genomic_DNA
EMBL
AC099676; CAH72278.2
; JOINED; Genomic_DNA
EMBL
BC080187; AAH80187.1
; -; mRNA
CCDS
CCDS53457.1; -. [P29536-1]
; .
PIR
S18732; S18732
; .
RefSeq
NP_036266.2; NM_012134.2. [P29536-1]
; .
UniGene
Hs.519075; -
; .
PDB
4Z79; X-ray
; 1.54 A; A=299-486
PDB
4Z8G; X-ray
; 2.10 A; A=364-486
PDB
4Z94; X-ray
; 2.40 A; G=364-486
PDBsum
4Z79; -
; .
PDBsum
4Z8G; -
; .
PDBsum
4Z94; -
; .
ProteinModelPortal
P29536; -
; .
SMR
P29536; -
; .
IntAct
P29536; 1
; .
STRING
9606.ENSP00000356257; -
; .
iPTMnet
P29536; -
; .
PhosphoSitePlus
P29536; -
; .
BioMuta
LMOD1; -
; .
DMDM
325511399; -
; .
MaxQB
P29536; -
; .
PaxDb
P29536; -
; .
PeptideAtlas
P29536; -
; .
PRIDE
P29536; -
; .
Ensembl
ENST00000367288; ENSP00000356257
; ENSG00000163431. [P29536-1]; .
GeneID
25802; -
; .
KEGG
hsa:25802; -
; .
UCSC
uc057oju.1; human. [P29536-1]
; .
CTD
25802; -
; .
DisGeNET
25802; -
; .
GeneCards
LMOD1; -
; .
HGNC
HGNC:6647; LMOD1
; .
HPA
HPA028325; -
; .
HPA
HPA028435; -
; .
HPA
HPA030097; -
; .
MIM
602715; gene
; .
neXtProt
NX_P29536; -
; .
OpenTargets
ENSG00000163431; -
; .
PharmGKB
PA30413; -
; .
eggNOG
KOG3735; Eukaryota
; .
eggNOG
ENOG410YAHM; LUCA
; .
GeneTree
ENSGT00760000119226; -
; .
HOGENOM
HOG000261624; -
; .
HOVERGEN
HBG006280; -
; .
InParanoid
P29536; -
; .
OMA
RNQTDKQ; -
; .
OrthoDB
EOG091G0C3H; -
; .
PhylomeDB
P29536; -
; .
TreeFam
TF315841; -
; .
Reactome
R-HSA-445355; Smooth Muscle Contraction
; .
ChiTaRS
LMOD1; human
; .
GenomeRNAi
25802; -
; .
PRO
PR:P29536; -
; .
Proteomes
UP000005640; Chromosome 1
; .
Bgee
ENSG00000163431; -
; .
CleanEx
HS_LMOD1; -
; .
ExpressionAtlas
P29536; baseline and differential
; .
Genevisible
P29536; HS
; .
GO
GO:0005884; C:actin filament
; ISS:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0016020; C:membrane
; TAS:ProtInc; .
GO
GO:0030016; C:myofibril
; IDA:UniProtKB; .
GO
GO:0030017; C:sarcomere
; ISS:UniProtKB; .
GO
GO:0045010; P:actin nucleation
; IDA:UniProtKB; .
GO
GO:0006936; P:muscle contraction
; TAS:Reactome; .
GO
GO:0051694; P:pointed-end actin filament capping
; IEA:InterPro; .
GO
GO:0030838; P:positive regulation of actin filament polymerization
; IDA:UniProtKB; .
Gene3D
3.80.10.10; -
; 1; .
InterPro
IPR032675; L_dom-like
; .
InterPro
IPR030136; LMOD1
; .
InterPro
IPR004934; TMOD
; .
InterPro
IPR003124; WH2_dom
; .
PANTHER
PTHR10901; PTHR10901
; 1; .
PANTHER
PTHR10901:SF25; PTHR10901:SF25
; 1; .
Pfam
PF03250; Tropomodulin
; 1; .
Pfam
PF02205; WH2
; 1; .
SMART
SM00246; WH2
; 1; .
PROSITE
PS51082; WH2
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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